Welcome to RMBase v3.0!

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RMBase v3.0 is an upgraded version of RMBase that mainly focuses on the mechanism and function of diverse RNA modifications. RMBase v3.0 is a comprehensive and convenient platform for efficient studying RNA modifications from large amounts of epitranscriptome high-throughput sequencing data. It provides multiple interfaces and web-based tools to integrate 73 types of RNA modification among 62 species, uncover the relationships between RNA modifications with a series of interacting factors, and reveal the distribution patterns, biochemical mechanisms, evolutionary conservation of RNA modifications and their biological roles in human diseases.

Finally, RMBase v3.0 provides three powerful web-based tools including modAnnotation, modMetagene and modGeneTool for custom analysis of RNA modification data.

The database idetified 1,074,100 RNA modification sites among 73 type of RNA modifications in 62 .

RMBase v3.0 Release Note (Oct 2023):

  • Species: 9 clades, 62 species.
  • Samples: 828 wild type datasets.
  • RNA Modification: 73 types.
  • Tools for RNA modifications: 3 tools.
  • Explore the pseudo sites guided by known and orphan snoRNAs. These pseudo sites occur on mRNA, rRNA, snRNA, tRNA, lncRNA and repeatMasker.
  • Detect the RNA modification clusters in genome wide.
  • Decipher the associated functions of RNA modifications with RBP, miRNA target, SNP, and SNV.
  • Identify novel m6A readers.
  • Explore the potential associations (co-localization) of histone modifications on RNA modifications.
  • Investigate the biological functions of RNA modifications in diverse cancers.

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© 2023, Qu Lab. School of Life Science, Sun Yat-sen University, China.
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