miRNA: all
CLIP-Data >= 1
Degradome-Data >= 0
pan-Cancer >= 0
programNum >= 1
program: None
target: PDCD4

The miRNA-mRNA Interactions Supported by Ago CLIP-seq Data

Download: EXCEL TXT
ClusterID miRNAID miRNA GeneID GeneName GeneType TargetSite(Narrow) narrowStart narrowEnd strand TargetSite(Broad) broadEnd PITA RNA22 miRmap microT miRanda PicTar TargetScan PITASeqStats RNA22SeqStats miRmapSeqStats microTSeqStats mirandaSeqStats pictarSeqStats TargetScanSeqStats TDMDScore AgoExpNum CleaveExpNum AGOStats AGOclipNum phyloP Pan-Cancer lineID
ClusterID miRNAID miRNA GeneID GeneName GeneType TargetSite(Narrow) narrowStart narrowEnd strand TargetSite(Broad) broadEnd PITA RNA22 miRmap microT miRanda PicTar TargetScan PITASeqStats RNA22SeqStats miRmapSeqStats microTSeqStats mirandaSeqStats pictarSeqStats TargetScanSeqStats TDMDScore AgoExpNum CleaveExpNum AGOStats AGOclipNum phyloP Pan-Cancer lineID

Description:

Here, we presented the miRNA-target interactions by intersecting the predicting target sites of miRNAs with binding sites of Ago protein, which were derived from CLIP-seq data.

We also introduced a new algorithm called TDMDScore to systematically scan the miRNA-target interactions and evaluated the potential interactions that triggered target-directed microRNA degradation (TDMD).

A higher TDMDScore indicates that the miRNA-target is more likely to trigger the TDMD.

You can search the interactions of miRNA-target by selecting one/multiple target-predicting programs (PITA, RNA22, miRmap, DIANA-microT, miRanda, PicTar and TargetScan).


Usage:

Select the miRNA: all
Select the target: PDCD4
Refine results with high stringency of CLIP Data: 3
Refine results with used Predicting Program: 2
Explore the interaction of miRNA-mRNA with Pan-Cancer analysis: 5
Users can filter the results by searching in the table. The searchable columns are allowed using comparison operators like ">=", "<=", ">", "<" and "=". The ">=" is set by default.